Which of these was the most significant event in the acceptance of Christianity in Roman Empire

Hello. You did not enter the answer options, but we can say that one of the most significant events in the acceptance of Christianity in the Roman empire was the issue of Edict of Milan.

Explanation:

After Emperor Constantine converted to Christianity, he issued the Edict of Milan, a document that proclaimed religious freedom within the Roman empire, thus officially ending all persecution of Christians who lived in the place in constant threat. This was one of the most important acts for the establishment of Christianity in Rome, making it the official religion in the region 10 years later.

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