How do scientist respond to experimental observations that don’t match current theories?

The results of the experimental observations should coincide with the facts of the current theories.

Explanation:

The scientific theory can be defined as the well defined as supported explanation for a natural phenomena. It is based upon the facts observed and also supported by the evidences obtained from the experimental trials.

If the experimental observations do not match with the concept of current scientific theory then the scientific either perform the experiment with the same scientific methodology or can switch to another scientific methodology to satisfy the facts of the current theories.