What are three ways in which tobacco use affects the respiratory system?

Is this question multiplc choice or open-ended? Anyways, I'll give you some ideas.
-Chronic obstructive pulmonary disease, a disease that gets worse over time and causes wheezing, shortness of breath, chest tightness, and other symptoms.
-Pneumonia
-Chronic Bronchitis, which causes swelling of the lining of your bronchial tubes. When this happens, less air flows to and from your lungs.

Neurotransmitters are messengers responsible for communication between neurons. they are released from synaptic vesicles and are received by receptors.  the communication is referred to as neurotransmission. the following statement is true about neurotransmitters: a. they're stored in synaptic vesicles in the axon.

Life, yes life it self madden