During dna replication, the 1. strand is synthesized in the 5′ to 3′ direction. the strand that runs away from the replication fork is synthesized in because. 3. 1.a)okazaki b)leading c)lagging 2.a)in fragments b)continuously c)without primers d)by rna polymerase 3.a)dna polymerase cannot synthesize in the 3' to 5' direction b)rna polymerase can only add primers to the leading strand c)dna polymerase cannot synthesize in the 5' to 3' direction d)rna polymerase can only add primers to the lagging strand