George developed alzheimer's disease well before the age of 60; early alzheimer's disease is associated with a condition that george was born with called

Early alzheimer’s disease is associated with the condition that George was born with called the trisomy 21. The trisomy 21 or also known as the down syndrome causes an individual to develop physical growth delays and causes a person to exhibit intellectual disability that could either be mild or moderate.

answer; /// i believe the correct answer is (b) disposition

explanation:

allergens: overstimulate the nerve system

neurotics: attack nerve cells

mutagens: damage or otherwise alter dna sequence

generators: cause defects during growth and development  

carcinogens: cause unchecked cell growth

i hope you get the idea according to me these are the effects that happened.