Which event is most closely associated with the beginning of the Protestant Reformation? The Act of Supremacy
the Diet of Worms
Luther's posting of the Ninety-five Theses
The Leipzig debate

Luther's posting of the Ninety-five Theses

Explanation:

Luther wrote a list of Ninety-five reasons he was against Catholicism, starting the Protestant Reformation.

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answer; software failure, and human error;