An investigator proposes to study a marketed product sold to treat high blood pressure in individuals over age 12 using a liquid formulation for children under age 12. The drug sponsor hopes that the information from the research can be used to change the labeling for use of the drug in younger children. Which of the following is the investigator's most appropriate course of action?

Submit the research protocol to the IRB for review and submit an IND application to the FDA before conducting the research
Discard the research protocol to the IRB for review and submit an IND application to the FDA before conducting the research
All of the above
none of the above

A). Submit the research protocol to the IRB for review and submit an IND application to the FDA before conducting the research.

Explanation:

As per the question, the most appropriate course of action for the investigator would be to 'Submit the research protocol to the IRB for review and submit an IND application to the FDA before conducting the research.' The investigator would be able to conduct the research only after receiving the necessary permissions as it concerns the lives of young children. Thus, study could be taken forward only after seeking the permission which requires the submission of protocols of the research to IRB and IND application to FDA. Hence, option A is the correct answer.

1. state-issued photo ids. provide them for free for those who can't afford them.

2. the system we have seems to be working nearly perfectly. seems like about 31 cases per billion votes cast

3. the national policy for hiring new employees which requires proof of eligibility to work. there are something like 20 types of identification which can be used for this.

this statement is true.

forests are public goods, available for everybody. when usage of such a good becomes interesting for consumers and its usage increases, there can be a risk of overexploitation. it is a non rival good therefore, if one person consumes the good it does not reduce the availability for subsequent consumers.

these caracteristics require the establishment of measures in order to prevent the destruction of a commonly owned space, for example, to restrict the amount of people that have access to the same time.