Charles has changed a great deal. He has a difficult time remembering things, even simple things like where he is or what year it is. He is having increasing difficulty understanding people or saying things that make sense to others. In addition, he rarely cleans himself anymore and acts in very inappropriate ways around others. Charles is exhibiting many signs of

Alzheimer's disease.

Explanation:

Alzheimer's disease is a disease that destroys memory of an individual, they begin to loose touch on things and people they primarily knew.

early settlements on the subcontinent. both the indus and the ganges rivers carried rich silt from the mountains to the plains. when the rivers flooded, the silt spread over the plains and made the soil in the river valleys fertile for farming.

"harry t. moore (1905-1951) – civil rights activist, leader, and the first martyr of the civil rights movement. fannie lou hamer (1917–1977) – leader in the american civil rights movement; co-founder of the national women's political caucus and freedom democratic party. james farmer (1920–1999) – congress of racial equality."