Which of the following significant changes to a protocol could be administratively approved (in principle) by vvc? a. a change from non-survival to survival surgeryb. a change in the principal investigatorc. a change in the specific objectives for the projectd. a change in the analgesic agent administered

“Why are we wasting energy trying to distinguish between a minor amendment and

a major amendment?” asked Joanie Green,

the new IACUC senior administrator at

Great Eastern University. It seemed to her

that if there was a request to add a procedure to a protocol it was to be considered

an amendment, nothing more or less. “Are

you saying that adding a small subcutaneous

implant is as important as adding a cardiac

valve replacement?” asked Bob Thorne, a

clinical veterinarian. Green responded that

it had nothing to do with the level of difficulty or risk to an animal, but whether

or not there was a need for IACUC review.

answer; theory of mind;