Which of the following is true about scientific inquiries? a. scientific inquiries are never based on previous scientific research and data. b. scientific inquiries are usually guided by previous scientific principles and knowledge. c. scientific inquiries usually do not require accuracy or precision when gathering data. d. scientific inquiries never require any mathematical knowledge or the application of mathematics.

Asubject in a clinical research trial experiences a serious, unanticipated adverse drug experience. how should the investigator proceed, with respect to the irb, after the discovery of the adverse event occurrence? a. do not report the adverse drug experience to the irb since it is a common adverse experience. b. report the adverse drug experience to the irb only if there are several other occurrences. c. report the adverse drug experience as part of the continuing review report. d. report the adverse drug experience in a timely manner, in keeping with the irb's policies and procedures, using the forms or the mechanism provided by the irb.