What are the advantages and disadvantages of the practice of direct democracy (initiatives, referendum, etc.) in state governments?

Asubject in a clinical research trial experiences a serious, unanticipated adverse drug experience. how should the investigator proceed, with respect to the irb, after the discovery of the adverse event occurrence? a. do not report the adverse drug experience to the irb since it is a common adverse experience. b. report the adverse drug experience to the irb only if there are several other occurrences. c. report the adverse drug experience as part of the continuing review report. d. report the adverse drug experience in a timely manner, in keeping with the irb's policies and procedures, using the forms or the mechanism provided by the irb.

Aspring has a natural length of 8 m. if a 12-n force is required to keep it stretched to a length of 10 m, how much work w is required to stretch it from 8 m to 16 m? (round your answer to two decimal places.)

On a geologic map, if the contacts between sedimentary rock units form a bull’s-eye pattern of concentric circles, with the youngest unit in the center, the underlying structure is a(n)