When is a zero considered significant?
check all that apply.
a. when it is to the right of the decimal point and it follows a non-
zero digit.
b. when it is to the left of the decimal point and no other digit is to
the left of the decimal point.
o
c. when it is between two digits.
o
d. when it is at the end of an integer that has no decimal point.

Asubject in a clinical research trial experiences a serious, unanticipated adverse drug experience. how should the investigator proceed, with respect to the irb, after the discovery of the adverse event occurrence? a. do not report the adverse drug experience to the irb since it is a common adverse experience. b. report the adverse drug experience to the irb only if there are several other occurrences. c. report the adverse drug experience as part of the continuing review report. d. report the adverse drug experience in a timely manner, in keeping with the irb's policies and procedures, using the forms or the mechanism provided by the irb.