Name three anatomical/physiological or biochemical reasons why the liver is a frequent target organ of many chemical-induced toxicities. Explain how the selective induction of either Phase I (oxidative enzymes - e. g., cytochrome P-450) or Phase II (conjugative enzymes - e. g., glutathione transferase) enzymes can increase the toxicity of some chemicals while decreasing the toxicities of others.

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You are assigned to care for david ramsey, a 22-year old male patient with back injury secondary to being thrown from a motorcycle. did nt damage the spinal, but the computed tomography revealed a compression fracture at l-2. david complains of severe back pain with numbness and tingling in the lower extremities. what assessments are indicated based on this nursing diagnosis? list other major nursing diagnoses based on david’s clinical presentation?

Anurse is preventing teaching to a client who has a new prescription for paroxetine. the nurse should instruct the client to monitor for which of the following adverse effects? a. peripheral edema b. alopecia c. tinnitus d. drowsiness