It is the hypothalamus that tells us when we are hungry or full. Its message is mediated by input from the gastrointestinal tract. There are also centers in the hypothalamus that regulate energy balance and metabolism based on the secretion of what hormones?

Corticotropin-releasing hormone (CRH): Oxytocin, TSH, TRH

Explanation:

Primary hormones secreted by the hypothalamus include:

Anti-diuretic hormone (ADH): This hormone increases water absorption into the blood by the kidneys.

Corticotropin-releasing hormone (CRH): CRH sends a message to the anterior pituitary gland to stimulate the adrenal glands to release corticosteroids, which help regulate metabolism and immune response.  

Gonadotropin-releasing hormone (GnRH): GnRH stimulates the anterior pituitary to release follicle stimulating hormone (FSH) and luteinizing hormone (LH), which work together to ensure normal functioning of the ovaries and testes.

Growth hormone-releasing hormone (GHRH) or growth hormone-inhibiting hormone (GHIH) (also known as somatostain): GHRH prompts the anterior pituitary to release growth hormone (GH); GHIH has the opposite effect. In children, GH is essential to maintaining a healthy body composition. In adults, it aids healthy bone and muscle mass and affects fat distribution.

Oxytocin: Oxytocin is involved in a variety of processes, such as orgasm, the ability to trust, body temperature, sleep cycles, and the release of breast milk.

Prolactin-releasing hormone (PRH) or prolactin-inhibiting hormone (PIH) (also known as dopamine): PRH prompts the anterior pituitary to stimulate breast milk production through the production of prolactin. Conversely, PIH inhibits prolactin, and thereby, milk production. Thyrotropin releasing hormone (TRH): TRH triggers the release of thyroid stimulating hormone (TSH), which stimulates release of thyroid hormones, which regulate metabolism, energy, and growth and development. 

the answer to your question is (pancreas).

answer:

it could come from a variety of sources.

explanation:

..although it was most likely developed through zoonotic transmission, where an infectious disease which usually afflicts when animals jump to humans.