In a pediatric clinic a study is carried out to see how effective aspirin is in reducing temperature. Twelve 5-year-old children suffering from influenza had their temperatures taken immediately before and 1 hour after administration of aspirin. The results are given below. Suppose we assume normality and want to test the hypothesis that aspirin is reducing the temperature.

Body temperature (°F) before and after taking aspirin Subject Before After Difference

Subect Before After Difference

1 102.4 99.6 2.8

2 103.2 100.1 3.1

3 101.9 100.2 1.7

4 103.0 101.1 1.9

5 101.2 99.8 1.4

6 100.7 100.2 0.5

7 102.5 101.0 1.5

8 103.1 100.1 3

9 102.8 100.7 2.1

10 102.3 101.1 1.2

11 101.9 101.3 0.6

12 101.4 100.2 1.2

Total 21