Mathematics
Mathematics, 17.10.2019 21:00, brainewashed11123

5. a patient is dosed with 1.5 mg/min of a new cancer therapy via iv. from past experiments, you determined that there are 2 compartments and that the ka from the central (i. e. blood compartment) is 0.39 h-1 and the k12 and k21 for flow to and back from the peripheral compartment are 0.49 h-2 and 2.42 h 1 respectively. you also measured the volumes of your two compartments and found that the central compartment has an effective volume of 124 l and the peripheral compartment has a volume of 250 l. a. diagram this 2 compartment system b. write out the differential equations describing the dosing in both compartments c. realizing that you don't have an interest in solving complex differential equations, you decide to determine the concentration time course numerically. generate a plot of the concentration in both compartments over a 10 h period (using euler's method) with a time step of 0.5 min. what is the approximate steady state concentration in the peripheral compartment.

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5. a patient is dosed with 1.5 mg/min of a new cancer therapy via iv. from past experiments, you det...

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