Although many businesses, including some very large corporations, have successfully merged the operations of a former competitor with their own, integrating a number of federal agencies, bureaus, and departments presented some unique challenges to the new Department of Homeland Security. In an essay of approximately 200 words, describe some of the critical challenges DHS addressed as they forged these many departments, bureaus and agencies into one. Use the DHS organizational chart as your guide.

Asubject in a clinical research trial experiences a serious, unanticipated adverse drug experience. how should the investigator proceed, with respect to the irb, after the discovery of the adverse event occurrence? a. do not report the adverse drug experience to the irb since it is a common adverse experience. b. report the adverse drug experience to the irb only if there are several other occurrences. c. report the adverse drug experience as part of the continuing review report. d. report the adverse drug experience in a timely manner, in keeping with the irb's policies and procedures, using the forms or the mechanism provided by the irb