Which time period in american history was marked by anti-immigrant sentiment?

In the years of 1840's, American history was first time marked by anti-immigrant sentiment and after that second time in the years of 1890's it was again marked.    

It was also marked by anti-immigrant in 2010. About three times American history was marked by anti-immigrant sentiment.  

So, these were three times when American history was marked by anti-immigrant sentiment.

b is correct

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