Why were the results of columbus first meeting with native americans in the west indies important?

The result of Columbus is the first meeting with Native American in the West Indies important because it had a serious far-reaching impact on native Americans.
Columbus was just one of many explorers sponsored by European monarchs in the 1400's who has an importance in trying to find a better, cheaper, faster route to Asia than their neighbors, in order to get an edge on the lucrative trade goods from the East Indies.