What must a presidential candidate achieve before running in the general election?

First the people must gain a nomination from their political party once this is done then they must earn majority of the seats in the electoral college

Cherokee  removal, part of the trail of tears, refers to the  forced  relocation between 1836 and 1839 of thecherokee  nation from  their lands ingeorgia, south carolina, north carolina, tennessee, texas, and alabama to the indian territory (present day oklahoma)  in  the thenwestern united states, and the resultant deaths