What famous work of edgar allan poe was published in 1841 and what was significant about it?

The murders in the rue morgue was published by Poe in 1841 it was famous because it was the first modern detective fiction story

Do you have more info about it ? i doubt this is the answer because i don't have all the information but if trouble was brewing in a clinic maybe it was an argument as to which clinic was better or smth of that nature