How did the Spanish most exploit the people of the Americas?

In many different ways, Spanish colonizers exploited the Native people of the Americas. Historical evidence proves that they mostly exploited them by: Enslaving in large numbers and importing them to Europe for slavery.  Mass killings & exterminations of Natives from their own homelands.

The Spanish colonization of the Americas began under the Crown of Castile, and was spearheaded by the Spanish conquistadors. The Americas were invaded and incorporated into the Spanish Empire, with the exception of Brazil, British America, and some small regions in South America and the Caribbean. The crown created civil and religious structures to administer this vast territory. The main motivations for colonial expansion were profit through resource extraction[1] and the spread of Catholicism through indigenous conversions.

Beginning with the 1492 arrival of Christopher Columbus in the Caribbean and gaining control over more territory for over three centuries, the Spanish Empire would expand across the Caribbean Islands, half of South America, most of Central America and much of North America. It is estimated that during the colonial period (1492–1832), a total of 1.86 million Spaniards settled in the Americas and a further 3.5 million immigrated during the post-colonial era (1850–1950); the estimate is 250,000 in the 16th century, and most during the 18th century as immigration was encouraged by the new Bourbon Dynasty

By contrast, the indigenous population plummeted by an estimated 80% in the first century and a half following Columbus's voyages, primarily through the spread of disease, forced labor and slavery for resource extraction, and missionization. This has been argued to be the first large-scale act of genocide in the modern era.

In the early 19th century, the Spanish American wars of independence resulted in the secession and subsequent division of most Spanish territories in the Americas, except for Cuba and Puerto Rico, which were lost to the United States in 1898, following the Spanish–American War. The loss of these territories ended Spanish rule in the Americas.

Explanation:

answer; i do believe that the (14th)fourteenth amendment is the correct answer

pacal the great: the throne was passed on to pacal through a female; as a result, he believed that he must legitimize his claim to the throne to add stability to his reign.

as a result, the daughter of ac kan's brother ruled until her son, pacal, reached an age old enough to assume the throne.

pacal the great became the king of the mayan city of palenque in a different way than most mayan kings.

pacal pointed out that ac kan had succeeded his mother as ruler, thereby establishing a precedent for the rule to pass through a female.  

he tried to justify that the way he gained the throne by connecting his mother with the divine mother and the mythological events that happened during the creation of the world.  

typically, the son of a male mayan ruler inherited the throne, but in 612 ce, king ac kan died and did not leave behind a male heir.

montezuma 1: even so, these wars of conquest failed to provide enough human sacrifices and because of this, he formed a triple alliance with cities in the valley of puebla-tlascala.  

in addition, montezuma realized that his government failed to the aztecs during the famine.

in order to appease him, montezuma increased the number of human sacrifices.

the aztec performed human sacrifices to their god huitzilopotchli because they believed he desired human blood.  

around 1440 ce, montezuma i became the fifth emperor of the aztecs and went on to rule for 28 years.  

soon after he assumed the throne, the aztecs were hit with a series of disasters, namely a plague of locusts, a flood, and a harsh frost  

huayna capac: huayna capac also fought to gain territories north of his empire in what is now ecuador.  

huayna capac significantly extended the inca empire to the south, into what is now argentina and chile.  

in 1493 ce, huayna capac became the eleventh ruler of the inca empire.  

huayna, therefore, wanted to gain his own lands and launched campaigns against tribes to the east and north of the empire.  

the inca empire reached its peak under the rule of huayna capac.

during this time the empire covered a vast territory including parts of present day colombia, peru, argentina, chile, bolivia, and ecuador.

during his reign, huayna heard about bearded men with pale skin that resembled the incan1 god viracocha and took this news as a bad omen.

huayna took this as another bad omen that predicted the destruction of the empire.