Who is Lady Montague and why is she a historic figure in inoculations? (smallpox)

An English aristocrat who wrote a series of letters from Turkey describing the procedure which is now called inoculation (ih not' you lay' shun). She had her son and then daughter publicly inoculated and its success became famous among British elite

Explanation:

Lady Mary Montagu was suffering through smallpox, a.k.a. “the speckled monster,” a disease that in her day — the early 18th century — was the deadliest on earth, eventually wiping out more people than the Black Plague. But today, somehow, it's gone. There hasn't been a case of smallpox reported in more than 40 years

location is the answer to this

the tallest building in the western hemisphere and the sixth tallest building in the world