The Trail of Tears most directly relates to which group?

It most directly relates to the Native Americans.

The Trail of Tears relates to Native American tribes who were forced to walk across the country in brutal weather, away from their land, to be resettled. The Cherokee and Seminoles, among others, were some of the affected tribes.

1 and 3

explanation:

learned it in 6th

a. because the u.s. was the leading with the most technology, economy, etc. also was teamed with other allies witch boosted the economy and materials to improve technology and use it.