Which state saw the first use of submarines in war?

virginia
louisiana
new york
south carolina

The state that saw the first use of submarine during the war is: South Carolina

The name of the Submarine is H.L Hunley, which was named after its inventor, Horace Lawson Hunley.
During its first attack, the submarine was managed to sunk the ships that used by the union to block Charleston harbor.

Do you have more info about it ? i doubt this is the answer because i don't have all the information but if trouble was brewing in a clinic maybe it was an argument as to which clinic was better or smth of that nature