In the 1500s, john calvin left france to

a escape religious persecution.
b become a catholic priest.
c translate the bible into german.
d stand trial at the diet of worms.

Hello!

The most suitable answer is

a. escape religious persecution.

John Calvin was a French theologian and reformer during the Protestan Reformation. On 1533, he became friend of Nocolas Cop, rector of the Paris University, and was invited to give an speech during an inaguration address. This speech strongly criticized the Church, so the King and the Chruch were furious at him and he had to leave Paris to save his life.  

Hope this helps.

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