Which factor played the largest role in the decline of the Byzantine Empire? A. The spread of the trade in the Bosporus Strait
B. The division of the Roman Empire
C. The rise of powerful Turkish empires
D. The joining of the Catholic and Orthodox churches

i think b

Explanation:

c

explanation:

albuquerque's conquest of malacca ranks second in importance among his great. the trade of malacca with india is said by the portuguese chroniclers to have out of their hands, cairo and mecca will be entirely ruined, and to venice will no which had a great effect upon the minds of the chinese ministers