This Columbian Exchange disease killed off one fifth of the Native population in the Americas

The disease component of the Columbian Exchange was decidedly one-sided. However, it is likely that syphilis evolved in the Americas and spread elsewhere beginning in the 1490s. More assuredly, Native Americans hosted a form of tuberculosis , perhaps acquired from Pacific seals and sea lions

Explanation:

The Columbian exchange, also known as the Columbian interchange, named after Christopher Columbus, was the widespread transfer of plants, animals, culture, human populations, technology, diseases, and ideas between the Americas, West Africa, and the Old World in the 15th and 16th centuries. It also relates to European colonization and trade following Christopher Columbus's 1492 voyage.

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