How did Native Americans react when the English settlers invaded their homeland? The Native Americans resisted.
The Native Americans ran away
The Native Americans did nothing
The Native Americans adopted all the English beleifs and customs.

Explanation:

the natives adopted the english customs and ways

president thomas jefferson commissioned the expedition shortly after the louisiana purchase in 1803 to explore and to map the newly acquired territory, to find a practical route across the western half of the continent, and to establish an american presence in this territory before britain and other european powers