What does the underlined pronoun refer to in this excerpt, and what effect does this usage have on Rousseau's message? "What we have just said confirms . . . That the depositaries of [people who are entrusted with] the executive power are not the people's masters, but its officers; that it can set them up and pull them down when it likes . . . ."

The constant presence of diseases or infectious agents within a given geographic area or population group. it may also refer to the usual prevalence of a given disease with such area or group. it includes holoendemic and hyperendemic diseases. a holoendemic disease is one for which a high prevalent level of infection begins early in life and affects most of the child population, leading to a state of equilibrium such that the adult population shows evidence of the disease much less commonly than do children (malaria in many communities is a holoendemic disease). a hyperendemic disease is one that is constantly present at a high incidence and/or prevalence rate and affects all groups equally. so probably family history.