The Italian Renaissance spread across Europe in the late 1400s through religion.
urbanization.
newspapers.
farming.

Urbanization

Explanation:

The Italian Renaissance spread across Europe in the late 1400s through Urbanization.

The Italian Renaissance began in Florence and it was characterized by a lot of architectural innovations and development In other sectors of life such as health , literature etc which were imitated in other parts of the country and world . In the 1500s printing became more profound and it was also useful in the spread.

while it was true that the cotton gin reduced the labor of removing seeds, it did not reduce the need for slaves to grow and pick the cotton.

explanation:

before eli whitney's invention of the cotton gin, picking and cleaning cotton was a slow, labor-intensive job. workers, usually slaves, had to pick the seeds from the cotton fibers by hand. this invention made it possible to grow large amounts of cotton on big farms and make money.