6. What does the last paragraph of the Declaration of Independence mean?

It means that America is no longer interested in being ruled by Britain and want to be independent.

the federalist party which advocated strong centralization dominated the united states government till 1800. so 1800 election transformed the power from one party to another party for the first time and was thus a turning point in american history. so jefferson called it "revolution of 1800".

explanation:

in mcculloch v. maryland (1819) the supreme court ruled that congress had implied powers under the necessary and proper clause of article i, section 8 of the constitution to create the second bank of the united states and that the state of maryland lacked the power to tax the bank.

gibbons v. ogden, (1824), was a landmark decision in which the supreme court of the united states held that the power to regulate interstate commerce, granted to congress by the commerce clause of the united states constitution, encompassed the power to regulate navigation.