Opposition to ratification of the constitution was based on the belief that it would

Weaken the states.

Explanation:

When it came time to ratify the Constitution, many states refused to do so. The main reason for this was the fact that these states believed that ratification of the Constitution would lead to the weakening of the states. They believed that the Constitution would provide too much power to the central government, and this would lead to the states being unable to act on their own affairs.

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