What factors do you think led Spain early dominance in the New world and in one particular region?

I'm no expert but considering the only other country capable of reaching it at the time was Portugal, who was focused on Africa, by the time Portugal arrived in Brazil Spain already dominated the carribean basin, England and France wouldnt arrive for a long time so it was pretty much just Spain, Spain and Portugal had also agreed how to split the findings in the new world

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there is no chart here so no one can answer this.