How did the transcontinental railroad impact life on the Great Plains?

The Transcontinental Railroad dramatically altered ecosystems. For instance, it brought thousands of hunters who killed the bison Native people relied on. The Cheyenne experience was different. The railroad disrupted intertribal trade on the Plains, and thereby broke a core aspect of Cheyenne economic life.

the  wilmot proviso  was designed to eliminate  slavery  within the  landacquired as a result of the mexican war (1846-48). fearing the addition of a pro-slave territory, pennsylvania congressman david  wilmot proposedhis amendment to the bill.

this is a good question! i'll do some research and come back when i have the answer!