Why was the plague especially frightening to people in medieval europe?

The viruses that cause herpes could protect against bacteria, including (at least in mice) the bubonic plague. The plague, or the Black Death, is caused by a microbe called Yersinia pestis. In the 14th century, this microscopic enemy killed off a third of Europe's population. I hope this is what your talking about

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The plague was especially frightening to people in medieval Europe for these reasons:

It was highly contagious.

Infected people died quickly after the onset of the first symptoms.

It had painful symptoms.

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