How did the invention of the steam locomotive and the clipper ship change the way American goods were marketed

The steam locomotive allowed for the transportation of goods at a much more rapid rate than by horse. The railroad let people know exactly where and when goods would arrive. The trains also gave the cargo a safer ride as it was much more difficult to rob a train than a horse drawn transport. As more railroads were built, products could travel farther than ever before in a timely manner. This brought down the cost of freight transport and increased profits for many businesses.

The constant presence of diseases or infectious agents within a given geographic area or population group. it may also refer to the usual prevalence of a given disease with such area or group. it includes holoendemic and hyperendemic diseases. a holoendemic disease is one for which a high prevalent level of infection begins early in life and affects most of the child population, leading to a state of equilibrium such that the adult population shows evidence of the disease much less commonly than do children (malaria in many communities is a holoendemic disease). a hyperendemic disease is one that is constantly present at a high incidence and/or prevalence rate and affects all groups equally. so probably family history.