What eventually led to conflicts between settlers and american indians in virginia?

The factor that eventually led to conflict between the European farmers destroying the soil with tobacco crops.

Explanation:

Tobacco was among the main crops that the Europeans cultivated. The increasing rate at which tobacco was being grown needed more land for the settlers.

Furthermore, tobacco easily depleted soil its nutrients therefore making it poor for food crops.

Since the Europeans needed more land for cultivation of Tobacco, they advanced into the native Indian land and had a lot of contact with native Indians defined by conflict.

The Indians were worried on the manner in which the Europeans were destroying their natural environment through killing game and falling trees to make space for cultivation.

The Indians were fed up with the above atrocities and successfully rose against the Europeans in Virginia in 1622 liberating themselves.

the answer is choice (b)