What was a major cause for the shift in european trade from the mediterranean sea to the atlantic ocean during the late 140os? (1) ottoman turks seized control of constantinople. (2) the ming dynasty authorized zheng he to make long-distance voyages. (3) the tokugawa shogunate adopted an isolationist policy. (4) christian crusaders captured jerusalem.

disease was the number one killer of native peoples. they had had little exposure to the diseases of europe. this led to some villages being almost completely wiped out and some tribes destroyed.

answer: the risk-return relationship. generally, the higher the potential return of an investment, the higher the risk. there is no guarantee that you will actually get a higher return by accepting more risk. diversification enables you to reduce the risk of your portfolio without sacrificing potential returns.

explanation:

the answer should be a. the sui empire, the tang empire extended from korea in the west to manchuria in the east.