What were the greatest causes of alexander the greats downfall

He might have contracted some tropical disease such as Malaria during his time in India, which might have proved fatal for his body, weakened by wounds during war and alcohol. His march through the Gedrosian desert, far away from water sources is what utterly 'destroyed' him.

- tobacco.

- "rolfe reacted to consumer demand by importing seed from the west indies and cultivating the plant in the jamestown colony. those tobacco seeds became the seeds of a huge economic empire.the tobacco economy rapidly began to shape the society and development of the colony. growing tobacco takes its toil on the soil."

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(1)representation based on state population (2)all states have equal representation apex