During infection, c. diphtheriae grows and multiplies within the upper respiratory tract. as each bacterial cell prepares for division the chromosome must be replicated so that each daughter cell receives a copy of the genetic information. the following statements summarize the major steps in replicating the bacterial chromosome. arrange the statements in the correct order to describe the process of replication of the leading strand.

The first event would be the unwinding of the double-stranded DNA by an enzyme called helicase. The next step will be the binding of specific proteins to the single strands, in order to stabilize them. Then the enzyme primase (which is a specific type of RNA polymerase) will synthesize an RNA primer. This RNA primer will be complementary to the DNA and will act as a template. This step is important because the enzymes that catalyze the formation of DNA strands, can only attach new nucleotides to an existing strand of nucleotides. Therefore, the next step will be the formation of a nucleotide strand by the DNA polymerase. DNA polymerase catalyzes formation of a sugar-phosphate bond neighboring nucleotides. Finally, hydrogen bonds are formed between the complementary bases. This will bind the two strands of nucleotides and create the double-stranded DNA molecule.

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