Alesion, or chancre, or open crater about the size of a dime is indicative of

This is a sign of the primary stage of syphilis. These lesions, or chancres, will show up in the exact spot that the bacteria originally entered the body. This is generally a sign of the infection. The illness often incubates for long periods of time, from between ten and ninety days, so it could be months from the original contact.