Aman who smokes one pack of cigarettes daily has been diagnosed with chronic bronchitis. he has been prescribed theophylline by his family doctor. what effect will the patient's smoking status have on the therapeutic use of theophylline?

Theophylline is known to interact with smoking. Stopping the smoking may lead to the aburpt increase in the serum concentration os theophylline, a toxicity might be caused. Polycystic hydrocarbons of smoke, increase theophylline clearance, which leads to a higher dose requirement of the drug, by the smokers. 

Answerfact;