Your middle-aged aunt says that she always feels more “tipsy” than her same-size husband, even though their alcohol intake is the same. you respond by saying to your aunt:

What I will say to my aunt is that, the reason why she became tipsy that her husband is because woman has less alcohol dehydrogenase enzyme compared to men. The alcohol dehyrdogenase enzyme are the ones responsible in conversion of alcohol with aldehyde and ketone. That is why women absorb more alcohol than men, making them more tipsy and feel drunk than of the men.