Aside from the adverse physical effects of street drugs, a consequence of substance abuse is that drugs

The mental affect of drugs on the brain. It affects memory, consciousness, decision making, and it changes the natural wiring of a brain.

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People who utilizes the progression principle will ensure their exercise program increases in frequency, intensity, time, and type. the changes need to happen gradually in order to ensure they make gains in their fitness program. a person who doesn't utilize the progression principle can still gain health benefits from exercising, but will not continue to improve in cardiovascular fitness.