In the revised monograph, this combined section details the most clinically significant safety concerns that affect decisions about whether to prescribe the drug.
a. indications and use
b. warnings and precautions
c. how supplied/storage and handling
d. dosage and administration

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People who utilizes the progression principle will ensure their exercise program increases in frequency, intensity, time, and type. the changes need to happen gradually in order to ensure they make gains in their fitness program. a person who doesn't utilize the progression principle can still gain health benefits from exercising, but will not continue to improve in cardiovascular fitness.