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Adouble-blinded trial for a new indication is conducted under an ind comparing two (2) marketed drugs, at twice the approved prescribed doses. on day 2, subject 603 had difficulty breathing. although it was life-threatening initially, subject 603 was treated and discharged directly from the emergency department after complete recovery. on day 5, subject 20 had a headache, which led to hospitalization and required blood pressure lowering medications. these episodes cannot be explained on the basis of the pharmacological property of either drug or the subjects' medical histories. the investigator would submit an sae report for: a. neither of the subjects b. subject 603 only c. subject 20 only d. both of the subjects

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Three of the statements below are true one is false. select the statement that is false. a. a decrease in glucose levels levels triggers an increase in secretion of glucagon by the pancreas. b. high cortisol levels generally cause a decrease in gnrh secretion by the hypothalamus. c. high estrogen levels in the blood will tend to decrease secretion of lh and fsh by the anterior pituitary. d. high igf-1 levels in the blood will tend to decrease growth hormone secretion by the anterior pituitary.