Health, 08.11.2020 19:00, janette32

Why platelet not active to clotting blood before we have injury?

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Platelets are not activated before an injury occurs because that activation is inhibited while they are circulating and there is no damage to the vacular wall.

Explanation:

Platelets are responsible for forming a haemostatic stopper, at the end of the blood coagulation process. These blood components have the ability to go to the place where the vessel wall is damaged and clump together to prevent blood from leaking out.

Platelet migration and activation occurs when the vascular wall endothelium is injured. When this happens, some substances are released - such as adrenaline, ADP and thromboxane A2, among others - and promote platelet activation.

However, this process should not occur before an injury occurs, as it can promote the formation of thrombi that can circulate in the blood vessels and block them.

An inhibitory mechanism, dependent on nitric oxide and prostaglandins, prevents platelets from being activated and clumping in the absence of injury.

answered: Guest

Can you explain it well?

answered: Guest

explanation:

two years ago, when picking flowers in the mountains back of yosemite valley, i found a book. it was blotted and storm-beaten; all of its outer pages were mealy and crumbly. the paper seemed to dissolve like the snow beneath which it had been buried, however; many of the inner pages were well preserved. and although all were more or less stained and torn, whole chapters were easily readable. this is the condition of the great open book of yosemite glaciers today; its granite pages have been torn and blurred by the same storms that wasted the castaway book.two years ago, when picking flowers in the mountains back of yosemite valley; i found a book. it was blotted and storm-beaten, all of its outer pages were mealy and crumbly. the paper seemed to dissolve like the snow beneath which it had been buried, however, many of the inner pages were well preserved. and although all were more or less stained and torn; whole chapters were easily readable. this is the condition of the great open book of yosemite glaciers today, its granite pages have been torn and blurred by the same storms that wasted the castaway book.