Which issue is related to long-term heroin use? pleasure
depression
hypoxia
mood swings

Depression (IT WAS NOT DEPRESSION IT WAS NOT DEPRESSION)

Explanation:

A synthetic drug, heroin is a highly dangerous substance which influences sedation when consumed. It causes individuals to feel an instant high, followed by reduced neurologic activity. However, for those with underlying mental health issues, heroin consumption can cause greater depressive states.

Additionally, after consistent consumption, depression is a significantly common side effect effecting most users. As a heroin addiction develops, individuals will experience lows as withdrawal symptoms set in. As greater consumption is maintained to avoid those lows, individuals are affecting their quality of life, causing chronic depressive and negative thoughts. Once a user loses control through a heroin addiction, whether a psychological disorder is present prior to first consumption or not, social isolation, suicidal thoughts and a rollercoaster of emotions are common.

the answer is anaerobic activities