Myasthenia gravis is a disease that is believed to be caused by autoimmune disorder, resulting in the loss of ACh receptors at the motor end plate of muscle fibers. Which of the following is likely to be a symptom of myasthenia gravis?

A. dehydration with headache
B. coma and loss of voluntary muscle movement
C. weakness of muscle
D. seizures and uncontrollable muscle movement

C. weakness of muscle

Explanation:

Myasthenia gravis is an autoimmune disorder where body's immune system attacks its own neuromuscular system.Antibodies destroy or block nicotinic acetylcholine receptors (ACh) which are present at neuromuscular junction. So, the neurons are not able to pass contraction signals to the muscle cells. As a result the muscles become weak. Hence the disease is characterized by weakness of muscle as evident by drooping eyes, difficulty in walking, talking and swallowing.  

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